Identifying Crohn's disease signal from variome analysis

Abstract

After years of concentrated research efforts, the exact cause of Crohn’s disease (CD) remains unknown. Its accurate diagnosis, however, helps in management and preventing the onset of disease. Genome-wide association studies have identified 241 CD loci, but these carry small log odds ratios and are thus diagnostically uninformative.

Publication
Genome Medicine
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Yanran Wang
PhD Candidate

Machine learning and sequencing data.